Acupuncture regulates the unfolded protein response and inhibits apoptosis in a rat model of heroin relapse.

Abstract

OBJECT To explore the unfolded protein response (UPR) in the hippocampus of rats undergoing heroin relapse and the mechanisms underlying the acupuncture-mediated inhibition of brain damage caused by heroin relapse. METHODS 60 Sprague-Dawley rats (30 females and 30 males) were randomly divided into four groups: Control group, Heroin group, Heroin… (More)
DOI: 10.1136/acupmed-2015-010954

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