Acupuncture mechanisms in rabbits studied with microinjection of antibodies against β-endorphin, enkephalin and substance P

@article{Jisheng1984AcupunctureMI,
  title={Acupuncture mechanisms in rabbits studied with microinjection of antibodies against β-endorphin, enkephalin and substance P},
  author={Han Ji-sheng and Xie Guo-xi and Zhou Zhong-fu and Ronnie Folkesson and Lars Terenius},
  journal={Neuropharmacology},
  year={1984},
  volume={23},
  pages={1-5}
}
Injection of protein-A purified antibodies against Met-enkephalin and beta-endorphin into the periaqueductal gray matter (PAG) was shown to decrease the analgesic effect of electroacupuncture (EA) in rabbits. Met-enkephalin antibodies were more potent than the beta-endorphin antibodies in causing a statistically-significant effect on electroacupuncture analgesia. Antibodies to Met-enkephalin were also active at the spinal level, whereas antibodies against beta-endorphin were without effect… CONTINUE READING

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