Acupuncture for allergic disease therapy – the current state of evidence

  title={Acupuncture for allergic disease therapy – the current state of evidence},
  author={Florian Pfab and Peter C Schalock and Vitaly Napadow and Georgios I Athanasiadis and Johannes Huss-Marp and Johannes Ring},
  journal={Expert Review of Clinical Immunology},
  pages={831 - 841}
This review summarizes current evidence for acupuncture treatment of allergies. Several randomized controlled trials have demonstrated a specific effect of acupuncture for allergic rhinitis; while a few studies have shown positive effects for atopic dermatitis, asthma and itch. Specifically for allergic rhinitis and asthma, acupuncture may be cost-effective in terms of money spent per quality-of-life gained. Acupuncture plays an increasingly important role as an evidence-based therapy for… 
Complementary and alternative medicine for allergic rhinitis : What is the evidence ?
Evaluated methods including acupuncture, immunotherapy and particular herbs have supportive evidence, but the efficacy of many other CAM is mostly controversial and possible side effects of different modalities remain unclear.
Efficacy of acupuncture in children with asthma: a systematic review
The results suggest that acupuncture may have a beneficial effect on PEF or PEF variability in children with asthma and large-scale RCTs are needed to further assess the efficacy of acupuncture in the treatment of asthma in children.
Acupuncture and its effect on cytokine and chemokine profiles in seasonal allergic rhinitis: a preliminary three-armed, randomized, controlled trial
In SAR, acupuncture reduces the intranasal unspecific inflammation, but does not seem to act immunologically on the Th1–Th2-imbalance, and leads to a lower nasal concentration than sham acupuncture or RM.
Assessment of Allergic Rhinitis among Children after Low-Level Laser Therapy
Laser acupuncture is a reliable, painless and non-invasive successful technique, which may be used as a complementary treatment for pediatric allergic rhinitis, especially in the group which receive laser acupuncture sessions.
Itch Management: Physical Approaches (UV Phototherapy, Acupuncture).
Non-randomised, uncontrolled studies and case series suggest that UV phototherapy is an effective treatment for itch associated with atopic dermatitis, and insufficient evidence exists to justify acupuncture as a physical therapy for itch.
Electro-acupuncture at Acupoint ST36 Ameliorates Inflammation and Regulates Th1/Th2 Balance in Delayed-Type Hypersensitivity
Electro-acupuncture treatment at acupoint ST36 relieved the pathological progression of DTH responses via reduction in footpad swelling, infiltration of inflammatory cells, levels of IgG and IgE as well as decreased production of IFN-γ and TNF-α in homogenized footpad tissue.
Alternative, Complementary, and Forgotten Remedies for Atopic Dermatitis
The evidence for a number of different alternative and complementary therapies, from textiles to vitamin supplements, is explored, hopeful that some show promising evidence that may one day lead to mainstream acceptance with further research.
Diet and atopic dermatitis.
Recent scientific data on the role of foods and dietary modifications in the management of atopic dermatitis as both an intervention and as prevention are reviewed.
Protective effect of electro-acupuncture on liver ischemia-reperfusion injury in rats.
It was demonstrated that electro-acupuncture protects the liver against I/R induced injury by inhibiting the inflammatory response, which is associated with the vagus.


The effect of acupuncture on allergic rhinitis: a randomized controlled clinical trial.
The effect of acupuncture on allergic rhinitis should be further evaluated in larger randomized studies after patients were randomized and assessed prior to treatment and then reassessed after 12 months.
Acupuncture in patients suffering from allergic asthma: is it worth additional costs?
Treating patients who have allergic bronchial asthma with acupuncture in addition to routine care resulted in additional costs and better effects in terms of patients' quality of life, and Acupuncture seems to be a useful and cost-effective add-on treatment.
Complementary therapy for atopic dermatitis and other allergic skin diseases: facts and controversies.
Considerations for Use of Acupuncture as Supplemental Therapy for Patients with Allergic Asthma
Acupuncture has regulatory effects on mucosal and cellular immunity in patients with allergic asthma and may be an adjunctive therapy for allergic asthma.
Acupuncture compared with oral antihistamine for type I hypersensitivity itch and skin response in adults with atopic dermatitis – a patient‐ and examiner‐blinded, randomized, placebo‐controlled, crossover trial
This study evaluated acupuncture and antihistamine itch therapy (cetirizine) on type I hypersensitivity itch and skin reaction in AD using a patient and examiner‐blinded, randomized, placebo‐controlled, crossover trial.
Review of complementary and alternative medicine in treatment of ocular allergies
Major complementary and alternative medicine modalities including herbal therapies, acupuncture, homeopathy, alternative immunotherapy and behavior modification are assessed for evidence of their effectiveness in the treatment of ocular allergy symptoms.
Acupuncture in patients with allergic rhinitis: a pragmatic randomized trial.
Cost-effectiveness for acupuncture in seasonal allergic rhinitis: economic results of the ACUSAR trial.
Effect of acupuncture in the treatment of seasonal allergic rhinitis: a randomized controlled clinical trial.
There was a significant improvement in FPS (nasal and non-nasal symptoms) between the two types of acupuncture treatments and no significant differences were shown in RMS between the realupuncture treatment group and the sham acupuncture treatment group.
Acupuncture in Patients With Seasonal Allergic Rhinitis
Acupuncture led to statistically significant improvements in disease-specific quality of life and antihistamine use measures after 8 weeks of treatment compared with sham acupuncture and with RM alone, but the improvements may not be clinically significant.