Actomyosin-driven left-right asymmetry: from molecular torques to chiral self organization.

@article{Naganathan2016ActomyosindrivenLA,
  title={Actomyosin-driven left-right asymmetry: from molecular torques to chiral self organization.},
  author={Sundar Ram Naganathan and Teije C Middelkoop and Sebastian F{\"u}rthauer and Stephan W Grill},
  journal={Current opinion in cell biology},
  year={2016},
  volume={38},
  pages={
          24-30
        }
}
Chirality or mirror asymmetry is a common theme in biology found in organismal body plans, tissue patterns and even in individual cells. In many cases the emergence of chirality is driven by actin cytoskeletal dynamics. Although it is well established that the actin cytoskeleton generates rotational forces at the molecular level, we are only beginning to understand how this can result in chiral behavior of the entire actin network in vivo. In this review, we will give an overview of actin… CONTINUE READING

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