Activity wheel running reduces escape latency and alters brain monoamine levels after footshock.

@article{Dishman1997ActivityWR,
  title={Activity wheel running reduces escape latency and alters brain monoamine levels after footshock.},
  author={Rod K. Dishman and Kenneth J. Renner and Shawn D. Youngstedt and Thomas G. Reigle and Bradford N. Bunnell and Kathleen A. Burke and Ho Sang Yoo and E. H. Mougey and J. L. Meyerhoff},
  journal={Brain research bulletin},
  year={1997},
  volume={42 5},
  pages={399-406}
}
We examined the effects of chronic activity wheel running on brain monoamines and latency to escape foot shock after prior exposure to uncontrollable, inescapable foot shock. Individually housed young (approximately 50 day) female Sprague-Dawley rats were randomly assigned to standard cages (sedentary) or cages with activity wheels. After 9-12 weeks, animals were matched in pairs on body mass. Activity wheel animals were also matched on running distance. An animal from each matched pair was… CONTINUE READING
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