Activity profiles of dalargin and its analogues in mu-, delta- and kappa-opioid receptor selective bioassays.

@article{Pencheva1999ActivityPO,
  title={Activity profiles of dalargin and its analogues in mu-, delta- and kappa-opioid receptor selective bioassays.},
  author={Nevena Pencheva and J Posp{\'i}sek and Linda Hauzerov{\'a} and Tomislav Barth and Peter Milanov},
  journal={British journal of pharmacology},
  year={1999},
  volume={128 3},
  pages={569-76}
}
1. To elucidate the structural features ensuring action of [D-Ala2, Leu5]-enkephalyl-Arg (dalargin), a series of dalargin analogues were tested for their effectiveness in depressing electrically-evoked contractions of the guinea-pig myenteric plexus-longitudinal muscle preparations (mu- and kappa-opioid receptors) and the vasa deferentia of the hamster (delta-opioid receptors), mouse (mu-, delta- and kappa-opioid receptors), rat (similar to mu-opioid receptors) and rabbit (kappa-opioid… CONTINUE READING