Activity profile of glutathione-dependent enzymes and respiratory chain complexes in rats supplemented with antioxidants and treated with carcinogens.

@article{Desai2001ActivityPO,
  title={Activity profile of glutathione-dependent enzymes and respiratory chain complexes in rats supplemented with antioxidants and treated with carcinogens.},
  author={Varsha G. Desai and Daniel A. Casciano and Ritchie J. Feuers and Anane Aidoo},
  journal={Archives of biochemistry and biophysics},
  year={2001},
  volume={394 2},
  pages={255-64}
}
Appropriate dietary interventions may reduce the potentially damaging effects of free radicals generated during metabolism and various physiological conditions. We have investigated the effects of dietary vitamins C, E, beta-carotene, or selenium (Se) on the activity of endogenous antioxidant enzymes and respiratory chain complexes in rats exposed to 7,12-dimethylbenz[a]anthracene (DMBA), a mammary carcinogen and bleomycin (BLM), an antineoplastic drug. These agents are known to generate DNA… CONTINUE READING

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