Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium.

@article{Zhu1991ActivityOT,
  title={Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium.},
  author={Naishuo Zhu and Baldomero M Olivera and John R. Roth},
  journal={Journal of bacteriology},
  year={1991},
  volume={173 3},
  pages={1311-20}
}
Transport of nicotinamide mononucleotide (NMN) requires two functions, NadI(T) and PnuC. The PnuC protein is membrane associated, as judged by isolation of active TnphoA gene fusions and demonstration that the fusion protein is membrane associated. The PnuC function appears to be the major component of the transport system, since mutant alleles of the pnuC gene permit NMN transport in the absence of NadI(T) function. We present evidence that the activity of the NMN transport system varies in… CONTINUE READING