Activity of the antimicrobial peptide P 34 against bovine alphaherpesvirus type 1

@inproceedings{Castro2017ActivityOT,
  title={Activity of the antimicrobial peptide P 34 against bovine alphaherpesvirus type 1},
  author={Clarissa Caetano de Castro and D{\'e}bora Scopel e Silva and G{\'e}ssica Arac{\'e}li Costa and Geferson Fischer and Gilberto D’avila Vargas and Adriano Brandelli and Marcelo Gonçalves de Lima and Amanda de Souza da Motta and S{\'i}lvia de Oliveira H{\"u}bner},
  year={2017}
}
Previous studies have demonstrated the antimicrobial activity of the peptide P34. In this study, the antiviral potential of P34 and the in vitro mechanism of action were investigated against bovine alphaherpesvirus type 1 (BoHV1). P34 exhibited low toxicity, a high selectivity index (22.9) and a percentage of inhibition of up to 100% in MDBK cells. Results… CONTINUE READING