Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.

@article{Manuel2016ActivityOM,
  title={Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.},
  author={Iv{\'a}n Manuel and Laura Lombardero and Frank M Laferla and Lydia Gim{\'e}nez-Llort and Rafael Rodr{\'i}guez-Puertas},
  journal={Neuroscience},
  year={2016},
  volume={329},
  pages={284-93}
}
Neurochemical alterations in Alzheimer's disease (AD) include cholinergic neuronal loss in the nucleus basalis of Meynert (nbM) and a decrease in densities of the M2 muscarinic receptor subtype in areas related to learning and memory. Neuromodulators present in the cholinergic pathways, such as neuropeptides and neurolipids, control these cognitive processes and have become targets of research in order to understand and treat the pathophysiological and clinical stages of the disease. This is… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Activity mediated by neurolipid (CB1 and LPA1) and neuropeptide (GAL1) receptors in a rat model with cholinergic basal forebrain lesion

A Llorente, E González de San Román, +3 authors R Rodrı́guez-Puertas
American Society for Neuroscience Meeting. Washington • 2014
View 3 Excerpts
Highly Influenced

A (1997a) Autoradiographic distribution of M1, M2, M3, and M4 muscarinic receptor subtypes in Alzheimer’s disease

R Rodrı́guez-Puertas, J Pascual, T Vilaró, Pazos
Synapse • 1997
View 3 Excerpts
Highly Influenced

1997b) 125I-galanin binding sites in Alzheimer’s disease: 706 Please cite this article in press as: Manuel I et al. Activity of muscarinic, galanin triple transgenic mice model of Alzheimer’s disease

R Rodrı́guez-Puertas, S Nilsson, J Pascual, A Pazos, T Hökfelt
2016

Anatomical location of LPA1 Please cite this article in press as: Manuel I et al. Activity of muscarinic, galanin triple transgenic mice model of Alzheimer’s disease

E González de San Román, I Manuel, +6 authors R Rodrı́guez-Puertas
2015
View 2 Excerpts

Similar Papers

Loading similar papers…