Activity of minocycline against Toxoplasma gondii infection in mice.

@article{Chang1991ActivityOM,
  title={Activity of minocycline against Toxoplasma gondii infection in mice.},
  author={Helena R. Chang and Rachel Comte and Pierre François Piguet and J. C. P{\'e}ch{\`e}re},
  journal={The Journal of antimicrobial chemotherapy},
  year={1991},
  volume={27 5},
  pages={639-45}
}
The chemotherapeutic activity of minocycline, a semi-synthetic tetracycline analogue, was evaluated in a murine model of toxoplasmosis. A lethal acute toxoplasmosis was produced by injecting 10(5) tachyzoites of the RH strain of Toxoplasma gondii into the peritoneal cavities of Swiss-Webster mice. When infected mice were treated once daily for 12 days… CONTINUE READING