Activity of lung neutrophils and matrix metalloproteinases in cyclophosphamide-treated mice with experimental sepsis.

Abstract

Sepsis in patients receiving chemotherapy may result in acute respiratory distress syndrome, despite decreased number of blood neutrophils [polymorphonuclear neutrophils (PMNs)]. In the present study, we investigated the correlation of cyclophosphamide (CY)-induced neutropenia with the destructive potential of lung PMN in respect to formation of septic… (More)

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@article{Hirsh2004ActivityOL, title={Activity of lung neutrophils and matrix metalloproteinases in cyclophosphamide-treated mice with experimental sepsis.}, author={Mark A. Hirsh and Julie Carmel and Viktoria Kaplan and Erella Livne and Michael Krausz}, journal={International journal of experimental pathology}, year={2004}, volume={85 3}, pages={147-57} }