Activity of glutathione-S-transferase in rat liver and kidneys after administration of lead or cadmium

The influence of an acute dose of lead nitrate or cadmium chloride on the activity of glutathione-S-trans-ferase (GST) was investigated in rats. CdCl2 (10 Μmol/kg) did not influence the enzyme activity in either organ. In contrast Pb(NO3)2 (100 Μmol/kg) caused a significant increase of GST activity in both organs. SDS polyacrylamide gel electrophoresis (SDS… CONTINUE READING