Activity of extracts of Kigelia pinnata against melanoma and renal carcinoma cell lines.

@article{Houghton1994ActivityOE,
  title={Activity of extracts of Kigelia pinnata against melanoma and renal carcinoma cell lines.},
  author={Peter John Houghton and Andrew Photiou and Shahzad Uddin and Prabodh V. Shah and Michael Browning and Steven Jac Todd Jackson and Spyros Retsas},
  journal={Planta medica},
  year={1994},
  volume={60 5},
  pages={
          430-3
        }
}
Serial dilutions of standardised water, ethanol, and dichloromethane extracts of the stembark and fruits of Kigelia pinnata were tested for their growth inhibitory effects against four melanoma cell lines and a renal cell carcinoma line (Caki-2) using two different (MTT and SRB) assays. Lapachol, a possible constituent of these extracts, together with known therapeutic antineoplastic agents, was also tested in the same way. The IC50 of each extract was measured after extracts were diluted to… CONTINUE READING
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