Activity of distamycin A on the induction of adaptive enzymes in Escherichia coli.

@article{Sanfilippo1966ActivityOD,
  title={Activity of distamycin A on the induction of adaptive enzymes in Escherichia coli.},
  author={Aurora Sanfilippo and E. Morvillo and Mario Ghione},
  journal={Journal of general microbiology},
  year={1966},
  volume={43 3},
  pages={
          369-74
        }
}
SUMMARY: We have studied the effect of distamycin A on the synthesis of inducible enzymes in Escherichia coli strain K12. Distamycin A did not inhibit the growth of E. coli K12 when the micro-organism already contained constitutive or inducible enzymes for the metabolism of sugars. The growth of E. coli was prevented when distamycin A was present during the enzymic induction. Distamycin A inhibited the formation of inducible β-galactosidase; the activity of the antibiotic was directly related… 

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ACTIVITY OF DISTAMYCIN A ON THE TRANSFER OF DRUG RESISTANCE IN GRAM‐NEGATIVE CLINICAL ISOLATES
  • A. Sanfilippo
  • Biology
    Annals of the New York Academy of Sciences
  • 1971
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