Activity of cecropin P1 and FA-LL-37 against urogenital microflora.

  title={Activity of cecropin P1 and FA-LL-37 against urogenital microflora.},
  author={V Smeianov and Karen Scott and Gregor Reid},
  journal={Microbes and infection},
  volume={2 7},
Two mammalian antimicrobial peptides, FA-LL-37 and cecropin P1, were tested for activity against six uropathogens and five Lactobacillus strains by broth microdilution assay. Both peptides inhibited Escherichia coli at 25 microM (FA-LL-39), and 1.56 microM (cecropin P1), Pseudomonas aeruginosa (12.5 microM, and 25 microM), and Klebsiella pneumoniae, (50 microM, and 1.56 microM), but not Enterococcus faecalis and Staphylococcus epidermidis. FA-LL-37 acted bacteriocidally against E. coli and… CONTINUE READING


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