Activity of amphotericin B, 5-fluorocytosine, and rifampin against six clinical isolates of Aspergillus.

@article{Kitahara1976ActivityOA,
  title={Activity of amphotericin B, 5-fluorocytosine, and rifampin against six clinical isolates of Aspergillus.},
  author={Masaki Kitahara and Viresh Seth and Gerald Medoff and George S. Kobayashi},
  journal={Antimicrobial agents and chemotherapy},
  year={1976},
  volume={9 6},
  pages={915-9}
}
Amphotericin B in combination with 5-fluorocytosine was synergistic against three clinical isolates of Aspergillus fumigatus and one of three clinical isolates of A. flavus. Amphotericin B in combination with rifampin was synergistic against all six clinical isolates of Aspergillus tested. The levels of 5-fluorocytosine and rifampin required for synergism were higher than clinically achievable concentrations when measurements of synergism were based on visual turbidity; but when the effects of… CONTINUE READING

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Combined effects of 5 - fluorocytosine and amphotericin B on Candida infections in mice

  • S. C. Salvin
  • J . Infect . Dis .
  • 1974

The combined effect of 5 - fluorocytosine and amphotericin B in the therapy of murine cryptotoccus

  • J. Carrizosa, M. E. Levison, T. Lawrence, D. Kaye
  • Proc . Soc . Exp . Biol . Med .
  • 1973

Synergistic action of amphotericin B and 5 - fluorocy - tosine against yeast - like organisms

  • G. S. Kobayashi, C. N. Kwan, P. Venkov
  • Proc . Soc . Expt . Biol . Med .
  • 1971

A new approach to amphotericin B therapy

  • M. Kitahara, V. K. Seth, G. Medoff
  • Am . J . Med .
  • 1968

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