Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons.

Abstract

Jun N-terminal kinase (JNK) is a multifunctional protein kinase crucial for neuronal apoptosis as well as neurite growth. We have previously shown that JNK activity is correlated with spiral ganglion neuron (SGN) apoptosis following hair cell loss in rats (Alam et al., 2007) implying that JNK inhibition may have therapeutic potential to protect SGNs in deaf… (More)
DOI: 10.1016/j.heares.2011.04.011

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