Activity of Pemetrexed on brain metastases from Non-Small Cell Lung Cancer.

@article{Bearz2010ActivityOP,
  title={Activity of Pemetrexed on brain metastases from Non-Small Cell Lung Cancer.},
  author={Alessandra Bearz and Isabella Garassino and M Tiseo and Orazio Caffo and Hector Soto-parra and Massimo Boccalon and Renato Talamini and A. Guijarro Santoro and Marco Bartolotti and Viviana Alejandra Murgia and Massimiliano Berretta and Umberto Tirelli},
  journal={Lung cancer},
  year={2010},
  volume={68 2},
  pages={
          264-8
        }
}
UNLABELLED Brain metastases from Non-Small Cell Lung Cancer are usually associated with poor prognosis and up to now chemotherapy has shown a modest activity upon cerebral localizations. We investigated the role of Pemetrexed, a new, well tolerated multi-target antifolate, on brain metastases. PATIENTS AND METHODS We collected 39 patients with evidence of cerebral nervous system (CNS) localizations from Non-Small Cell Lung Cancer (NSCLC) before starting treatment with Pemetrexed as second… CONTINUE READING
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