Activity of Lac repressor anchored to the Escherichia coli inner membrane

  title={Activity of Lac repressor anchored to the Escherichia coli inner membrane},
  author={Boris G{\"o}rke and Jana Reinhardt and Bodo Rak},
  journal={Nucleic Acids Research},
  pages={2504 - 2511}
The transient inactivation of gene regulatory proteins by their sequestration to the cytoplasmic membrane in response to cognate signals is an increasingly recognized mechanism of gene regulation in bacteria. It remained to be shown, however, whether tethering to the membrane per se could be responsible for inactivation, i.e. whether such relocation leads to a spatial separation from the chromosome that results in inactivity or whether other mechanisms are involved. We, therefore, investigated… CONTINUE READING

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