Corpus ID: 29749283

Activity of 17 beta-hydroxy-3-aza-A-homo-4 alpha-androsten-4-one-p-N, N-bis(2-chloroethyl)aminophenoxyacetate (NSC-620480) in P388 leukemia. Activity of steroidal lactams in Ehrlich tumor.

@article{Catsoulacos1990ActivityO1,
  title={Activity of 17 beta-hydroxy-3-aza-A-homo-4 alpha-androsten-4-one-p-N, N-bis(2-chloroethyl)aminophenoxyacetate (NSC-620480) in P388 leukemia. Activity of steroidal lactams in Ehrlich tumor.},
  author={P. Catsoulacos and G. Pairas},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={1990},
  volume={12 7},
  pages={
          501-5
        }
}
  • P. Catsoulacos, G. Pairas
  • Published 1990
  • Medicine
  • Methods and findings in experimental and clinical pharmacology
  • A new homo-aza-steroidal ester, 17 beta-hydroxy-3-aza-A-homo-4 alpha-androsten-4-one-p-N,N-bis(2-chloroethyl)aminophenoxyaceta te gives a T/C greater than 125% in the treatment of P388 lymphoid leukemia. Modified and unmodified steroids without alkylating congener have been studied for activity in L1210 leukemia and EAT cells. 
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