Activity-induced regulation of myosin isoform distribution: comparison of two contractile activity programs.

@article{Diffee1993ActivityinducedRO,
  title={Activity-induced regulation of myosin isoform distribution: comparison of two contractile activity programs.},
  author={Gary M. Diffee and Vincent J. Caiozzo and Samuel A. McCue and R. E. Herrick and Kenneth M. Baldwin},
  journal={Journal of applied physiology},
  year={1993},
  volume={74 5},
  pages={2509-16}
}
This study examined the role of specific types of contractile activity in regulating myosin heavy chain (MHC) isoform expression in rodent soleus. A combination of hindlimb suspension (SN) and two programmed contractile training activity paradigms, either isometric contractile activity (ST-IM) or high-load slowly shortening isovelocity activity, were utilized. Both training paradigms increased muscle mass compared with SN alone. However, only ST-IM resulted in a partial prevention of the… CONTINUE READING
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