Activity-induced changes in synaptic release sites at the crayfish neuromuscular junction.

@article{Wojtowicz1994ActivityinducedCI,
  title={Activity-induced changes in synaptic release sites at the crayfish neuromuscular junction.},
  author={J. Martin Wojtowicz and Leo Marin and Harold L. Atwood},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1994},
  volume={14 6},
  pages={3688-703}
}
Crustacean motor axons provide a model in which activity-dependent changes in synaptic physiology and synaptic structure can be concurrently observed in single identifiable neurons. In response to a train of stimulation, crustacean neuromuscular junctions undergo pronounced facilitation of transmitter release. The effects of maintained high-frequency stimulation may persist for at least several hours ("long-term facilitation"). Electrophysiological studies suggest that the number of "active… CONTINUE READING

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