Activity-independent intracellular Ca2+ oscillations are spontaneously generated by ventral spinal neurons during development in vitro.

@article{Fabbro2007ActivityindependentIC,
  title={Activity-independent intracellular Ca2+ oscillations are spontaneously generated by ventral spinal neurons during development in vitro.},
  author={Alessandra Fabbro and Beatrice Pastore and Andrea Nistri and Laura Ballerini},
  journal={Cell calcium},
  year={2007},
  volume={41 4},
  pages={317-29}
}
Within the CNS, distinct neurons may rely on different processes to modulate cytosolic Ca2+ depending on the network developmental phase. In particular, in the immature spinal cord, synchronous electrical discharges are coupled with biochemical signals triggered by intracellular Ca2+ waves. Nevertheless, the presence of neuronal-specific Ca2+ elevations independent from synaptic activity within mammalian spinal networks has not yet been described. The present report is the first description of… CONTINUE READING

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