Activity-guided isolation of saponins from Kalopanax pictus with anti-inflammatory activity.

@article{Li2002ActivityguidedIO,
  title={Activity-guided isolation of saponins from Kalopanax pictus with anti-inflammatory activity.},
  author={Da Wei Li and Eun Bang Lee and S. Kang and J. Hyun and W. Whang},
  journal={Chemical \& pharmaceutical bulletin},
  year={2002},
  volume={50 7},
  pages={
          900-3
        }
}
By bioassay-guided separation, a known saponin, kalopanaxsaponin A (1) and a new saponin, pictoside A (2) were isolated from the stem bark of Kalopanax pictus as anti-inflammatory components when evaluated by vascular permeability test. Another novel saponin, pictoside B (3) was also isolated but was inactive in the test system used. The structures of pictosides A and B were elucidated as caulophyllogenin 3-O-alpha-L-rhamnopyranosyl(1-->2)-alpha-L-arabinopyranoside (2) and pictogenin (3beta… Expand
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Five new compounds, kalopanaxsaponin G (2) and kalopanaxins A (6), B (8), C (11) and D (13), were isolated from the bark of Kalopanax pictus together with nine known compounds, kalopanaxsaponins AExpand
Saponins from the roots ofPulsatilla koreana
From the roots ofPulsatilla koreana, three monodesmosides(pulsatilla saponins A, B and D) and two bisdesmosides(pulsatilla saponins F and H) were isolated. The structure of these saponins have beenExpand
Structure de la chrysantelline B, nouvelle saponine isolée de Chrysanthellum procumbens Rich
Structure of Chrysantellin B, a New Saponin Isolated from Chrysanthellum procumbens Rich A new saponin, chrysantellin B, has been found in a tropical plant Chrysanthellum procumbens Rich as aExpand
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TLDR
The results suggest that the methanol extract of Kalopanax pictus bark has an anti-inflammatory activity which is distributed in the ethyl acetate fraction. Expand
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Five new triterpene saponins, leonticins D-H, were isolated from the tubers of Leontice kiangnanensis. Based on a combination of chemical degradation and spectroscopic analysis (negative ion FAB massExpand
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TLDR
Results suggest that anti-rheumatoidal effects of KPS-A and -I contribute to the inhibition of kinin formation by suppression of trypsin inhibitor activity. Expand
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Two new triterpenoid glycosides called medicago-saponins P1 (1) and P2 (2) were isolated together with five known glycosides from the aerial parts of Medicago polymorpha L. (Leguminosae). TheExpand
New Triterpenes from the Leaves of Timonius timon
TLDR
Two new triterpenes have been isolated from the leaves of Timonius timon (Rubiaceae) with other known compounds: 3β,6β,19,23- tetrahydroxyuts-12-en- 28-oic acid, 3-O-[β-D-quinovopyranosyl]quinovic acid, and loganin. Expand
Kalopanaxsaponin A from Kalopanax pictus, a potent antioxidant in the rheumatoidal rat treated with Freund's complete adjuvant reagent.
TLDR
Results suggested that Kalopanaxsaponin-A, extracted from K. pictus, could reduce rheumatoidal syndromes through antioxidative mechanisms. Expand
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