Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere

@article{Bartolo2014ActivitydependentSP,
  title={Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere},
  author={Paola De Bartolo and Fulvio Florenzano and Lorena Burello and Francesca Gelfo and Laura Petrosini},
  journal={Brain Structure and Function},
  year={2014},
  volume={220},
  pages={2895-2904}
}
The environmental enrichment (EE) paradigm is widely used to study experience-dependent brain plasticity. In spite of a long history of research, the EE influence on neuronal morphology has not yet been described in relation to the different regions of the cerebellum. Thus, aim of the present study was to characterize the EE effects on density and size of dendritic spines of Purkinje cell proximal and distal compartments in cerebellar vermian and hemispherical regions. Male Wistar rats were… CONTINUE READING

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