Activity-dependent refinement of inhibitory connections.

@article{Sanes1993ActivitydependentRO,
  title={Activity-dependent refinement of inhibitory connections.},
  author={Dan H. Sanes and Christiane Takacs},
  journal={The European journal of neuroscience},
  year={1993},
  volume={5 6},
  pages={
          570-4
        }
}
Several lines of evidence suggest that excitatory synaptic transmission contributes to the maturation of precise neuronal connections. In the present study we determined whether the specific innervation pattern of single inhibitory arborizations was dependent upon neuronal activity during development. A homogeneous group of glycinergic inhibitory neurons in the central auditory system, the medial nucleus of the trapezoid body (MNTB), was functionally denervated in neonatal gerbils. The… CONTINUE READING
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