Activity and turnover of eosinophil and neutrophil granulocytes are altered in visceral leishmaniasis.

@article{Elshafie2011ActivityAT,
  title={Activity and turnover of eosinophil and neutrophil granulocytes are altered in visceral leishmaniasis.},
  author={Amir Ibrahim Elshafie and Erik Hlin and Lena Douhan H{\aa}kansson and Gehad E.B. Elghazali and Sayda Hassan El Safi and Johan R{\"o}nnelid and Per Venge},
  journal={International journal for parasitology},
  year={2011},
  volume={41 3-4},
  pages={463-9}
}
Visceral leishmaniasis (VL) is a health issue in Sudan. Our aim was to investigate the involvement of eosinophils and neutrophils in VL by serum and plasma measurements of eosinophil cationic protein (ECP) and myeloperoxidase (MPO) and some key cytokines and chemokines. Blood was collected from 125 VL patients and 181 healthy Sudanese controls from the same rural area. Results showed reduced eosinophil and neutrophil counts in the VL group (P=0.0001 and P=0.002, respectively). Serum-ECP levels… CONTINUE READING