Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions.

@article{Langford2010ActivityAT,
  title={Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions.},
  author={Melanie L. Langford and Sahar Hasim and Kenneth W. Nickerson and A. O. L. Atkin},
  journal={Antimicrobial agents and chemotherapy},
  year={2010},
  volume={54 2},
  pages={940-2}
}
Farnesol interacts with Candida albicans as both a quorum-sensing molecule and toxic agent, but confusion abounds regarding which conditions promote these distinct responses. Farnesol sensitivity was measured when inoculum cell history and size, temperature, and growth media were altered. Parameters for farnesol tolerance/sensitivity were defined, validating previous studies and identifying new variables, such as energy availability. This study clearly defines what farnesol concentrations are… CONTINUE READING

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