Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.

@article{Harkin1999ActivityAO,
  title={Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.},
  author={Andrew J Harkin and John P. J. Kelly and Mairead Mcnamara and Thomas J. Connor and Kate Dredge and Anna M Redmond and Brian E. Leonard},
  journal={European journal of pharmacology},
  year={1999},
  volume={364 2-3},
  pages={
          123-32
        }
}
The limitations of antidepressant drugs to treat depression has warranted ongoing research to identify pharmacological agents and strategies which offer a faster onset of action and greater therapeutic efficacy. Noradrenaline and serotonin are widely reported to be involved in the mechanism of action of antidepressants and the recent development of selective reuptake inhibitors of these transmitters has provided the opportunity to determine the effects of targeting these transmitter systems… CONTINUE READING

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