Activity and excitability of Renshaw cells in non-decerebrate and decerebrate cats

@article{Benecke2004ActivityAE,
  title={Activity and excitability of Renshaw cells in non-decerebrate and decerebrate cats},
  author={Renate Benecke and C. Hellweg and Justus Meyer-Lohmann},
  journal={Experimental Brain Research},
  year={2004},
  volume={21},
  pages={113-124}
}
SummaryThe effects of pre- and/or intercollicular decerebration on the activity and responsiveness of individual Renshaw cells were studied in 15 adult cats under continuous light anesthesia. It was found that decerebration either had no effect on the spontaneous activity of Renshaw cells and their response to antidromic stimulation, or it enhanced activity, provided that the blood pressure was prevented from falling below critical values. Spontaneous activity showed the more pronounced… 
Responses of Renshaw cells coupled with hindlimb extensor motoneurons to sinusoidal stimulation of labyrinth receptors in the decerebrate cat
TLDR
In conclusion, R-cells linked with the GS mot oneurons displayed an α-pattern of response during low frequency head rotation, suggesting that they were largely activated by the recurrent collaterals of the corresponding motoneurons driven by the VS volleys.
Tetanus toxin induced actions on spinal Renshaw cells and Ia-inhibitory interneurones during development of local tetanus in the cat
TLDR
Results indicate that the central action of tetanus toxin in local tetanus does not consist of a general loss of postsynaptic inhibition, and it is suggested that tetanus toxins acts mainly on synaptic elements of the alpha- and gamma-motoneurones or on presynaptic nerve terminals in their vicinity.
Fatigue‐related depression of the feline monosynaptic gastrocnemius–soleus reflex
TLDR
A fatigue‐related suppression of Ia excitation of synergistic motoneurones, probably arising from the activation of group III and IV afferents is demonstrated.
Recurrent inhibition of individual Ia inhibitory interneurones and disinhibition of their target α-motoneurones during muscle stretches
TLDR
The findings suggest that normal orthodromic activation of Renshaw cells, and consequently the recurrent inhibition of the Ia inhibitory interneurones, is predominantly linked with rapid phasic, rather than slow tonic, motoneuronal firing.
Responses of Renshaw cells to muscle ramp stretch
TLDR
The results lend some support to the hypothesis that RCs are triggered predominantly by large phasic mot oneurones, and the smaller tonic motoneurones seem to provide some supporting background input to the RCs.
Effects of type a botulinum toxin on the cholinergic transmission at spinal renshaw cells and on the inhibitory action at ia inhibitory interneurones
TLDR
It is suggested that on the spinal level the central action of botulinum toxin predominantly passes on the motoneurones.
Changes in neuronal properties and spinal reflexes during development of spasticity following spinal cord lesions and stroke: studies in animal models and patients.
  • H. Hultborn
  • Biology, Psychology
    Journal of rehabilitation medicine
  • 2003
TLDR
The results of animal studies on the sensory control of and the transmitter systems involved in the spinal locomotor centers are now being used to improve rehabilitation of walking in persons with spinal cord injury and hemiplegia.
Animal Experiments on the Spinal Action of Midazolam
TLDR
A decisive disadvantage of this high-dose long-term therapy of spasticity or tetanus intoxication with diazepam is its long half-life with systemic application, which can lead to hang-over symptoms for some days and in some cases to comatose conditions.

References

SHOWING 1-10 OF 19 REFERENCES
Die Erregung der Renshaw-Zellen durch reflektorische Entladungen der α-Motoneurone
TLDR
It is concluded that the discharge of motoneurones is the main spring for the firing of Renshaw cells following orthdromic stimulation of ipsilateral muscle afferents.
Unitary activity of spinal interneurones of cats
TLDR
The majority of the responses described in this paper were probably recorded from axons and therefore might have been led off from fibres belonging to long descending pathways, but this limitation does not apply to responses obtained after very short central times but cannot be ruled out in other instances.
Central effects of centripetal impulses in axons of spinal ventral roots.
TLDR
Information concerning this activity is presented at this time because of its possible importance in the economy of the ventral gray matter and, more particularly, because the pattern of discharge of the individual neurons is sufficiently unusual to be of general interest.
Disinhibition der Extensor-Motoneurone nach intercolliculärer Dezerebrierung
TLDR
It is concluded that the higher excitability of extensor motoneurones in the decerebrate state is correlated with disinhibition, which implies that spasticity is not based merely on the release of fusimotor activity.
Pathophysiology of Muscle Tone
TLDR
Experimental Models of Disorders of Muscle Tone with Particular Reference to the Role of the Gamma-System and Spasticity and Rigidity and a Brief Survey on Evaluation of Muscle tone in Motor Disorders.
SPASTICITY AND RIGIDITY: AN EXPERIMENTAL STUDY AND REVIEW
  • G. Rushworth
  • Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1960
With the introduction of the word "tonus" by Mueller in 1838 to describe the slight contractil tension of muscles when at rest, an era of investigation began which was beset with difficulties from
MUSCLE TONE: I. EXTENSIBILITY OF MUSCLES IN DECEREBRATE RIGIDITY
TLDR
The curve of extensibility obtained when weights are plotted on the abscissae and elongations on the ordinates is not a straight line but a curve, which Wertheimer subsequently recognized as a hyperbola.
ÉTUDE EXPÉRIMENTALE DE L'HYPERRÉFLEXIE TENDINEUSE EN CLINIQUE NEUROLOGIQUE
TLDR
One misses discussions of more modern techniques such as the use of radioactively labelled substances for studying, say, the morphogenesis of the nervous system in this 'outof-date' textbook.
Die Transformation des Entladungsmusters der Renshaw-Zellen bei tetanischer antidromer Reizung
  • J. Haase
  • Biology
    Pflüger's Archiv für die gesamte Physiologie des Menschen und der Tiere
  • 2004
TLDR
Die Beziehungen zwischen antidromer Reizfrequenz und Repetitionsstärke der Renshaw-Zellen können durch die elektrophysiologischen Eigenschaften dieser Zellen ausreichend erklärt werden and verbessern das Verständnis f for die recurrente Inhibition.
...
1
2
...