Activities of hepatic and extrahepatic microsomal mixed function oxidase enzymes in diabetic and gonadectomized-diabetic rats.

@article{AlTurk1981ActivitiesOH,
  title={Activities of hepatic and extrahepatic microsomal mixed function oxidase enzymes in diabetic and gonadectomized-diabetic rats.},
  author={Walid A. Al-Turk and Sidney J Stohs and E B Roche},
  journal={General pharmacology},
  year={1981},
  volume={12 5},
  pages={
          345-50
        }
}
Abstract 1. 1. Streptozotocin (STZ)-induced diabetes results in a decrease in hepatic aryl hydrocarbon hydroxylase (AHH) activity in male rats and an increase in female rats, while hepatic 7-ethoxycoumarin 0-deethylase (ECD) activity is increased in both sexes. 2. 2. In castrated male rats, induction of the diabetic state resulted in a further decrease in hepatic AHH activity. In diabetic female rats, ovariectomy did not alter hepatic AHH or ECD activities. 3. 3. STZ-induced diabetes produced… CONTINUE READING

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