Activin signaling balances proliferation and differentiation of ovarian niche precursors and enables adjustment of niche numbers.


How the numbers of niches and resident stem cells within a particular organ are determined during development and how they may be modulated or corrected is a question with significant medical implications. In the larval ovary of Drosophila melanogaster, somatic precursors for niches, and germ cells that will become germline stem cells, co-develop. Somatic… (More)
DOI: 10.1242/dev.113902

8 Figures and Tables


  • Presentations referencing similar topics