Activin-binding protein is present in pituitary.

  title={Activin-binding protein is present in pituitary.},
  author={Katsuhisa Kogawa and Tatsuji Nakamura and Kentaro Sugino and Koji Takio and Koiti Titani and Hiromu Sugino},
  volume={128 3},
A binding protein for activin was purified from bovine pituitary by affinity chromatography on dextran sulfate-Sepharose CL-4B and activin-Affi-Gel 10. A 52,700-fold purification over the starting crude homogenate was achieved. The purified preparation showed two bands of 36 and 33 kilodalton in sodium dodecyl sulfate-polyacrylamide gel electrophoresis under nonreducing conditions. The ability of each form of the protein to specifically bind activin was determined by ligand blot analysis and… CONTINUE READING


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