Activin and inhibin, estrogens and NFκB, play roles in ovarian tumourigenesis is there crosstalk?

@article{Drummond2012ActivinAI,
  title={Activin and inhibin, estrogens and NFκB, play roles in ovarian tumourigenesis is there crosstalk?},
  author={Ann E. Drummond and Peter J. Fuller},
  journal={Molecular and cellular endocrinology},
  year={2012},
  volume={359 1-2},
  pages={85-91}
}
Ovarian cancer may be the most frequently lethal gynaecological malignancy but the heterogeneous nature of the disease and the advanced stage at which it is usually diagnosed, have contributed to the paucity of information relating to its aetiology and pathogenesis. Members of the TGF-β superfamily, estrogen and NFκB have all been implicated in the development and progression of cancers from a wide range of tissues. In the ovary, TGF-β superfamily members and estrogen play key roles in… CONTINUE READING
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