Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14.

@article{Salogni2009ActivinAI,
  title={Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14.},
  author={Laura Salogni and Tiziana Musso and Daniela Bosisio and Massimiliano Mirolo and Venkatakrishna R Jala and Bodduluri Haribabu and Massimo Locati and Silvano Sozzani},
  journal={Blood},
  year={2009},
  volume={113 23},
  pages={5848-56}
}
Activin A is a dimeric protein, member of the transforming growth factor (TGF)-beta family that plays a crucial role in wound repair and in fetal tolerance. Emerging evidence also proposes activin A as a key mediator in inflammation. This study reports that activin A induces the directional migration of immature myeloid dendritic cells (iDCs) through the… CONTINUE READING