Activin A in brain injury.

  title={Activin A in brain injury.},
  author={Pasquale Florio and Diego Gazzolo and Stefano Vincenzo Luisi and Felice Petraglia},
  journal={Advances in clinical chemistry},
Activin A is a growth factor composed of two betaA subunits belonging to the transforming growth factor beta (TGF-beta) superfamily of dimeric proteins. The biological activity of activin A is mediated by two different types of receptors, the type I (ARI and ARIB) and the type II receptors (ARII and ARIIB), and by two activin-binding proteins, follistatin and follistatin-related gene. These factors bind to activin A and thereby inhibit its biological effects. Activin A, its receptors, and… CONTINUE READING