Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse.

@article{Ruiz2011ActiveZA,
  title={Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse.},
  author={Roc{\'i}o Ruiz and Raquel Cano and Juan Jos{\'e} Casa{\~n}as and Michael A. Gaffield and William J. Betz and Lucia Tabares},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 6},
  pages={2000-8}
}
Synchronous neurotransmitter release is a highly regulated process that takes place at specializations at the presynaptic membrane called active zones (AZs). The relationships between AZs, quantal release, and vesicle replenishment are not well understood in a mature synapse. We have measured the number, distribution, and other properties of AZs in mouse motor nerve terminals and combined these observations with electrophysiological estimates of the size of the readily releasable pool (RRP) of… CONTINUE READING

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