Active urea transport and an unusual basolateral membrane composition in the gills of a marine elasmobranch.

@article{Fines2001ActiveUT,
  title={Active urea transport and an unusual basolateral membrane composition in the gills of a marine elasmobranch.},
  author={G A Fines and James Ballantyne and Patricia A Wright},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2001},
  volume={280 1},
  pages={R16-24}
}
In elasmobranch fishes, urea occurs at high concentrations (350-600 mM) in the body fluids and tissues, where it plays an important role in osmoregulation. Retention of urea by the gill against this huge blood-to-water diffusion gradient requires specialized adaptations to the epithelial cell membranes. Experiments were performed to determine the mechanisms and structural features that facilitate urea retention by the gill of the spiny dogfish Squalus acanthias. Analysis of urea uptake by gill… CONTINUE READING
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