Active transmembrane drug transport in microgravity: a validation study using an ABC transporter model [v1; ref status: indexed,]


Microgravity has been shown to influence the expression of ABC (ATP-Binding Cassette) transporters in bacteria, fungi and mammals, but also to modify the activity of certain cellular components with structural and functional similarities to ABC transporters. Changes in activity of ABC transporters could lead to important metabolic disorders and undesired… (More)


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