Active surveillance for Vibrio cholerae O1 and vibriophages in sewage water as a potential tool to predict cholera outbreaks.

@article{Madico1996ActiveSF,
  title={Active surveillance for Vibrio cholerae O1 and vibriophages in sewage water as a potential tool to predict cholera outbreaks.},
  author={Guillermo Madico and William Checkley and Robert H. Gilman and Nieves Bravo and Lilia Cabrera and Maritza Calderon and Ana Ceballos},
  journal={Journal of clinical microbiology},
  year={1996},
  volume={34 12},
  pages={2968-72}
}
The 1991 Peruvian cholera epidemic has thus far been responsible for 600,000 cholera cases in Peru. In an attempt to design a cholera surveillance program in the capital city of Lima, weekly sewage samples were collected between August 1993 and May 1996 and examined for the presence of Vibrio cholerae O1 bacteria and V. cholerae O1 bacteriophages (i.e., vibriophages). During the 144 weeks of surveillance, 6,323 cases of clinically defined cholera were recorded in Lima. We arbitrarily defined an… CONTINUE READING