Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.

@article{Yamakoshi2003ActiveOS,
  title={Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.},
  author={Y. Yamakoshi and N. Umezawa and A. Ryu and K. Arakane and N. Miyata and Y. Goda and T. Masumizu and T. Nagano},
  journal={Journal of the American Chemical Society},
  year={2003},
  volume={125 42},
  pages={
          12803-9
        }
}
To characterize fullerenes (C(60) and C(70)) as photosensitizers in biological systems, the generation of active oxygen species, through energy transfer (singlet oxygen (1)O(2)) and electron transfer (reduced active oxygen radicals such as superoxide anion radical O(2)(-)* and hydroxyl radical *OH), was studied by a combination of methods, including biochemical (DNA-cleavage assay in the presence of various scavengers of active oxygen species), physicochemical (EPR radical trapping and near… Expand
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