Active immunization with a Coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection.

@article{Cai2013ActiveIW,
  title={Active immunization with a Coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection.},
  author={Yicun Cai and Qingwei Liu and Xulin Huang and Dapeng Li and Zhiqiang Ku and Yunfang Zhang and Zhong Huang},
  journal={Vaccine},
  year={2013},
  volume={31 18},
  pages={2215-21}
}
Coxsackievirus A16 (CA16) is one of the main pathogens that cause hand, foot and mouth disease, which frequently occurs in young children. A small percentage of patients infected with CA16 may suffer from severe neurological complications that could also lead to death. Recent epidemiological data shows the increase in both the total number and the incidence rate of severe CA16-associated cases in China, indicating that CA16 should be targeted for vaccine development. In this article, we report… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 38 references

Severe handfootandmouth disease caused by mixed infection of enterovirus 71 and coxsackie A 16 : reports of 6 cases

W Zhang, YG Wang, +8 authors YL Zhang
Chin Gen Pract • 2011

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