Active immunization against tumor necrosis factor-alpha decreases proinflammatory cytokines, oxidative stress mediators and adhesion molecules risk factors in streptozotocin-induced diabetic rats.

@article{Tuorkey2013ActiveIA,
  title={Active immunization against tumor necrosis factor-alpha decreases proinflammatory cytokines, oxidative stress mediators and adhesion molecules risk factors in streptozotocin-induced diabetic rats.},
  author={Muobarak Jaber Tuorkey and Karolin Kamel Abdul-Aziz and Abdel-Aziz A. Zidan},
  journal={Endocrine, metabolic & immune disorders drug targets},
  year={2013},
  volume={13 3},
  pages={
          269-74
        }
}
UNLABELLED Diabetes is now one of the most common un-communicable diseases worldwide. Few studies have dealt specifically with the potential therapeutic effect of TNF-α suppressor to decrease oxidative stress markers in patients with diabetes. The aim of this study was to investigate the potential therapeutic and toxic effect of the direct injection of the anti-TNF-α on oxidative stress mediators, proinflammatory cytokines and vascular risk factors associated with diabetes on diabetic rats… CONTINUE READING

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