Active hair bundle motion linked to fast transducer adaptation in auditory hair cells.

@article{Ricci2000ActiveHB,
  title={Active hair bundle motion linked to fast transducer adaptation in auditory hair cells.},
  author={Anthony J Ricci and Andrew C. Crawford and Robert Fettiplace},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 19},
  pages={7131-42}
}
During transduction in auditory hair cells, hair bundle deflection opens mechanotransducer channels that subsequently reclose or adapt to maintained stimuli, a major component of the adaptation occurring on a submillisecond time scale. Using a photodiode imaging technique, we measured hair bundle motion in voltage-clamped turtle hair cells to search for a mechanical correlate of fast adaptation. Excitatory force steps imposed by a flexible glass fiber attached to the bundle caused an initial… CONTINUE READING
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