Active contraction of cardiac muscle: in vivo characterization of mechanical activation sequences in the beating heart.

@article{Tsamis2011ActiveCO,
  title={Active contraction of cardiac muscle: in vivo characterization of mechanical activation sequences in the beating heart.},
  author={Alkiviadis Tsamis and Wolfgang Bothe and John-Peder Escobar Kvitting and Julia C. Swanson and D. C. Miller and Ellen Kuhl},
  journal={Journal of the mechanical behavior of biomedical materials},
  year={2011},
  volume={4 7},
  pages={1167-76}
}
Progressive alterations in cardiac wall strains are a classic hallmark of chronic heart failure. Accordingly, the objectives of this study are to establish a baseline characterization of cardiac strains throughout the cardiac cycle, to quantify temporal, regional, and transmural variations of active fiber contraction, and to identify pathways of mechanical activation in the healthy beating heart. To this end, we insert two sets of twelve radiopaque beads into the heart muscle of nine sheep; one… CONTINUE READING
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