Active and passive membrane properties of rat sympathetic preganglionic neurones innervating the adrenal medulla.

@article{Wilson2002ActiveAP,
  title={Active and passive membrane properties of rat sympathetic preganglionic neurones innervating the adrenal medulla.},
  author={Jennifer M M Wilson and Elaine Coderre and Leo P. Renaud and D Spanswick},
  journal={The Journal of physiology},
  year={2002},
  volume={545 Pt 3},
  pages={945-60}
}
The intravascular release of adrenal catecholamines is a fundamental homeostatic process mediated via thoracolumbar spinal sympathetic preganglionic neurones (AD-SPN). To understand mechanisms regulating their excitability, whole-cell patch-clamp recordings were obtained from 54 retrogradely labelled neonatal rat AD-SPN. Passive membrane properties included a mean resting membrane potential, input resistance and time constant of -62 +/- 6 mV, 410 +/- 241 MOmega and 104 +/- 53 ms, respectively… CONTINUE READING
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