Active Touch and Self-Motion Encoding by Merkel Cell-Associated Afferents

@article{Severson2017ActiveTA,
  title={Active Touch and Self-Motion Encoding by Merkel Cell-Associated Afferents},
  author={Kyle S. Severson and Duo Xu and Margaret Van de Loo and Ling Bai and David D Ginty and Daniel H. O’Connor},
  journal={Neuron},
  year={2017},
  volume={94},
  pages={666-676.e9}
}
Touch perception depends on integrating signals from multiple types of peripheral mechanoreceptors. Merkel-cell associated afferents are thought to play a major role in form perception by encoding surface features of touched objects. However, activity of Merkel afferents during active touch has not been directly measured. Here, we show that Merkel and unidentified slowly adapting afferents in the whisker system of behaving mice respond to both self-motion and active touch. Touch responses were… CONTINUE READING