Active Poliovirus Baked From Scratch

@article{Couzin2002ActivePB,
  title={Active Poliovirus Baked From Scratch},
  author={Jennifer Couzin},
  journal={Science},
  year={2002},
  volume={297},
  pages={174 - 175}
}
  • J. Couzin
  • Published 12 July 2002
  • Biology
  • Science
With mail-order DNA and more than 2 years of painstaking work, researchers for the first time have assembled a virus from its chemical code. The lab-built poliovirus, described online this week by Science , killed mice and was almost indistinguishable from the original. Biologists disagree on how difficult it would be to construct far bulkier viruses such as smallpox to create bioweapons. 
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References

REPORTS: Chemical Synthesis of Poliovirus cDNA: Generation of Infectious Virus in the Absence of Natural Template Jeronimo Cello

  • American Association for the Advancement of Science. All Rights Reserved
  • 2002