Active Poliovirus Baked From Scratch
@article{Couzin2002ActivePB,
title={Active Poliovirus Baked From Scratch},
author={J. Couzin},
journal={Science},
year={2002},
volume={297},
pages={174 - 175}
}With mail-order DNA and more than 2 years of painstaking work, researchers for the first time have assembled a virus from its chemical code. The lab-built poliovirus, described
online
this week by
Science , killed mice and was almost indistinguishable from the original. Biologists disagree on how difficult it would be to construct far bulkier viruses such as smallpox to create bioweapons.
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References
REPORTS: Chemical Synthesis of Poliovirus cDNA: Generation of Infectious Virus in the Absence of Natural Template Jeronimo Cello
- American Association for the Advancement of Science. All Rights Reserved
- 2002