Active Microphase Separation in Mixtures of Microtubules and Tip-Accumulating Molecular Motors

  title={Active Microphase Separation in Mixtures of Microtubules and Tip-Accumulating Molecular Motors},
  author={Bezia Lemma and Noah P. Mitchell and Radhika Subramanian and Daniel J. Needleman and Zvonimir Dogic},
  journal={Physical Review X},
Mixtures of filaments and molecular motors form active materials with diverse dynamical behaviors that vary based on their constituents ’ molecular properties. To develop a multiscale of these materials, we map the nonequilibrium phase diagram of microtubules and tip-accumulating kinesin-4 molecular motors. We find that kinesin-4 can drive either global contractions or turbulentlike extensile dynamics, depending on the concentrations of both microtubules and a bundling agent. We also observe a… 

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